Projects per year
Personal profile
Personal Statement
I have always had a great interest in Science and Engineering because of the impacts that both of these have on our daily lives. Working in pharmaceutical secondary manufacturing brings together both disciplines. Secondary manufacturing focuses on the conversion of the active drugs into products suitable for administration. Combining pilot plant and modelling resarch, we work on the introduction of continuous technology instead to traditional batch equipment. Transition to continuous is challenging but it will reduce the time of production of the drugs besides to create safer and cheaper drugs .
Research Interests
My new role takes place at the new Medicines Manufacturing Innovation Centre (MMIC) , where I am part of a team focused in the development a continuous direct compression (CDC) platform. CDC is a continuous manufacturing process that allows much greater process control than traditional batch-type pharmaceutical manufacturing methods. Its advantages include rapid production of formulations at a range of scales and also shorter optimisation times compared to batch-type processes. In my role, I will also help to develop a digitally-twinned CDC platform that allows us to understand and optimise the formulation process in digital space. The hope is that this reduces the amount of starting materials needed for optimisation and reduce the overall cost of the technology for the end-user.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Master in Science, Newcastle University
Award Date: 30 Sep 2013
Master of Engineering, Universidade de Santiago de Compostela
Award Date: 29 Jun 2012
Keywords
- MMIC
- Direct compression
- Formulation
- Modelling
Network
Projects
- 2 Finished
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David Begg / NSF Studentship | Mendez Torrecillas, Carlota
Halbert, G., Robertson, J. & Mendez Torrecillas, C.
1/10/14 → 4/06/19
Project: Research Studentship - Internally Allocated
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Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Mendez Torrecillas, Carlota
Halbert, G., Robertson, J. & Mendez Torrecillas, C.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/14 → 4/06/19
Project: Research Studentship - Internally Allocated
Research output
- 2 Article
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The impact of channel fill level on internal forces during continuous twin screw wet granulation
Torrecillas, C. M., Gorringe, L. J., Rajoub, N., Robertson, J., Elkes, R. G., Lamprou, D. A. & Halbert, G. W., 28 Dec 2018, (E-pub ahead of print) In: International Journal of Pharmaceutics. p. 1-43 43 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)8 Downloads (Pure) -
A novel methodology to study polymodal particle size distributions produced during continuous wet granulation
Mendez Torrecillas, C., Halbert, G. W. & Lamprou, D. A., 15 Mar 2017, In: International Journal of Pharmaceutics. 519, 1-2, p. 230-239 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)78 Downloads (Pure)
Thesis
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Process and product understanding of rapid and continuous wet granulation
Author: Mendez Torrecillas, C., 4 Jun 2019Supervisor: Halbert, G. (Supervisor) & Robertson, J. (Supervisor)
Student thesis: Doctoral Thesis
Activities
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A Novel Metrology for Polymodal Particle Size Distributions and Its Beyond Application in Twin Screw Granulation
Carlota Mendez (Speaker)
26 Apr 2018Activity: Talk or presentation types › Oral presentation
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A Novel Metrology for Polymodal Particle Size Distributions and Its Beyond Application in Twin Screw Granulation
Carlota Méndez Torrecillas (Speaker)
26 Apr 2018Activity: Talk or presentation types › Oral presentation