Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides

Wu Su, Clive R. Bagshaw, Glenn A. Burley

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We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-directional FRET is enhanced by the complete assembly of each of the constituent parts, resulting in the selective routing of light along simple DNA duplexes as well as a three-way junction (3WJ).

Original languageEnglish
Article number1883
Number of pages6
JournalScientific Reports
Publication statusPublished - 24 May 2013


  • ninding
  • nanotechnology
  • hairpin polyamide
  • photonic wires
  • origami
  • arrays
  • proteins
  • minor-grrove

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