Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw

Camila Macaúbas-Silva, Maysa D. G. Félix, Ana Karoline S. de Aquino, Paulo G. Pereira-Júnior, Emmily Vieira de O. Brito, Abrahão A. de Oliveira-Filho, John O. Igoli, David G. Watson, Yanna C. F. Teles

Research output: Contribution to journalArticlepeer-review

Abstract

Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.
Original languageEnglish
Pages (from-to)2424-2428
Number of pages5
JournalNatural Product Research
Volume35
Issue number14
Early online date4 Oct 2019
DOIs
Publication statusPublished - 18 Jul 2021

Keywords

  • Psidium guineense Sw.
  • araçain
  • 2-(4-hydroxyphenyl)ethyl hexanoate
  • Klebsiella pneumoniae

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