Abstract
A polymer microfluidic device for the formation of artificial bilayer lipid membranes (BLMs) on-chip is described. The device is fabricated from thin, transparent films of poly(methyl methacrylate), allowing for optical monitoring of the BLM. In addition, detection of single fluorescently-labeled lipid molecules using conventional epifluorescence microscopy is described.
| Original language | English |
|---|---|
| Article number | 47 |
| Pages (from-to) | 252-257 |
| Number of pages | 6 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 5838 |
| DOIs | |
| Publication status | Published - 9 Dec 2005 |
| Event | Nanotechnology II - Seville, Spain Duration: 9 May 2005 → 11 May 2005 |
Keywords
- lipid bilayers
- microfluidics
- rapid fabrication
- single molecule detection
- microscopic examination
- plastic films
- polymethyl methacrylates
- thin films
- fluidic devices