Co-Cr wear particles and cobalt ions stimulate the expression of human general toxicology related genes on monocyte like U937 cells

Olga Maria Posada Estefan, Rothwelle Tate, Mary Grant

Research output: Contribution to conferencePosterpeer-review


Cobalt-chromium (Co-Cr) particles in the nanometre size range are produced by wear at the articulating surfaces of metal-on-metal implants, and are associated with inflammation, bone loss and implant loosening.
Original languageEnglish
Publication statusPublished - 7 Apr 2013
EventBritish Toxicology Society Meeting - Solihull, United Kingdom
Duration: 7 Apr 201310 Apr 2013


ConferenceBritish Toxicology Society Meeting
Country/TerritoryUnited Kingdom


  • cobalt ions
  • metal on metal wear
  • toxicology

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