Improved biotransformations on charged PEGA supports

A Basso, L De Martin, L Gardossi, G Margetts, I Brazendale, A Y Bosma, R V Ulijn, S L Flitsch

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26 Citations (Scopus)

Abstract

PEGA supports functionalised with permanent charges show superior swelling properties in aqueous media when compared to neutral PEGA; a novel positively charged PEGA resin significantly improves penicillin G amidase (PGA) catalysed biotransformation on solid support, by favouring accessibility of the negatively charged enzyme.

Original languageEnglish
Pages (from-to)1296-1297
Number of pages2
JournalChemical Communications
Issue number11
Early online date7 May 2003
DOIs
Publication statusPublished - 2003

Keywords

  • biotransformations
  • charged PEGA supports
  • swelling properties
  • aqueous media
  • neutral PEGA

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