LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation

Fiona McKenzie; Karen Faulds; Duncan Graham

doi:10.1039/b802163e

LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation

Fiona McKenzie, Karen Faulds, Duncan Graham

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

Original language	English
Pages (from-to)	2367-2369
Number of pages	3
Journal	Chemical Communications (London)
Issue number	20
DOIs	https://doi.org/10.1039/b802163e
Publication status	Published - 28 May 2008

Keywords

oligonucleotide
optical detection
helix formation
polynucleotides

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10.1039/b802163e

1 Finished

NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture
Birch, D., Dawson, M., Faulds, K., Girkin, J., Graham, D., Martin, R., O'Donnell, K., Rolinski, O., Smith, W. & Wynne, K.
Scottish Funding Council SFC, EPSRC (Engineering and Physical Sciences Research Council)
1/08/08 → 31/01/12
Project: Research

Cite this

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title = "LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation",

abstract = "Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.",

keywords = "oligonucleotide, optical detection, helix formation, polynucleotides",

author = "Fiona McKenzie and Karen Faulds and Duncan Graham",

year = "2008",

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doi = "10.1039/b802163e",

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pages = "2367--2369",

journal = "Chemical Communications (London)",

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AU - McKenzie, Fiona

AU - Faulds, Karen

AU - Graham, Duncan

PY - 2008/5/28

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N2 - Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

AB - Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

KW - oligonucleotide

KW - optical detection

KW - helix formation

KW - polynucleotides

U2 - 10.1039/b802163e

DO - 10.1039/b802163e

M3 - Article

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JO - Chemical Communications (London)

JF - Chemical Communications (London)

SN - 0009-241X

IS - 20

ER -

LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation

Abstract

Keywords

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Projects

NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture

Cite this