The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

K.H. Smith, A.B. Jozwiak, D.V. Bax, C.M. Kielty, R.A. Black

    Research output: Contribution to journalConference Contributionpeer-review

    80 Citations (Scopus)


    The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.
    Original languageEnglish
    Pages (from-to)1762
    JournalTissue Engineering
    Issue number7
    Publication statusPublished - 2007


    • cellular response
    • polyurethane surface
    • vascular extracellular matrix proteins
    • vascular graft
    • cells

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