The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

K.H. Smith; A.B. Jozwiak; D.V. Bax; C.M. Kielty; R.A. Black

doi:10.1089/ten.2007.1501

The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

K.H. Smith, A.B. Jozwiak, D.V. Bax, C.M. Kielty, R.A. Black

Research output: Contribution to journal › Conference Contribution › peer-review

80 Citations (Scopus)

Abstract

The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.

Original language	English
Pages (from-to)	1762
Journal	Tissue Engineering
Volume	13
Issue number	7
DOIs	https://doi.org/10.1089/ten.2007.1501
Publication status	Published - 2007

Keywords

cellular response
polyurethane surface
vascular extracellular matrix proteins
vascular graft
cells

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10.1089/ten.2007.1501

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title = "The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft",

abstract = "The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.",

keywords = "cellular response, polyurethane surface, vascular extracellular matrix proteins, vascular graft, cells",

author = "K.H. Smith and A.B. Jozwiak and D.V. Bax and C.M. Kielty and R.A. Black",

note = "Also presented at Tissue Engineering and Regenerative Medicine International Society TERMIS-EU Chapter Meeting, 2007",

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language = "English",

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The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft. / Smith, K.H.; Jozwiak, A.B.; Bax, D.V.; Kielty, C.M.; Black, R.A.

In: Tissue Engineering, Vol. 13, No. 7, 2007, p. 1762.

Research output: Contribution to journal › Conference Contribution › peer-review

TY - JOUR

T1 - The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

AU - Smith, K.H.

AU - Jozwiak, A.B.

AU - Bax, D.V.

AU - Kielty, C.M.

AU - Black, R.A.

N1 - Also presented at Tissue Engineering and Regenerative Medicine International Society TERMIS-EU Chapter Meeting, 2007

PY - 2007

Y1 - 2007

N2 - The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.

AB - The aim of this work is to develop an artificial artery for use in bypass surgery. The hybrid artery consists of a porous tubular scaffold made from a polyurethane elastomer. The surface of the polymer is then modified with recombinant proteins in order to encourage the growth of organised layers of vascular cells.

KW - cellular response

KW - polyurethane surface

KW - vascular extracellular matrix proteins

KW - vascular graft

KW - cells

UR - http://www.ssbii.org.uk/ssbii9/abstract_book/session_5/ssbii9_abstract_smith.pdf

U2 - 10.1089/ten.2007.1501

DO - 10.1089/ten.2007.1501

M3 - Conference Contribution

VL - 13

SP - 1762

JO - Tissue Engineering

JF - Tissue Engineering

SN - 1076-3279

IS - 7

ER -

The cellular response to a polyurethane surface modified with vascular extracellular matrix proteins - towards the development of a cell-seeded small-diameter vascular graft

Abstract

Keywords

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